13 results
Fungal biomarkers
Beta-d-glucan
Aspergillus galactomannan

By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com]

#ID  #Infectious Diseases  #Infections
#Differential #Ddx
Sara Dong @swinndong ... febrilepodcast.com] #ID #Infectious ... Diseases #Infections ... #Differential # ... Ddx #Diagnosis #
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
Most invasive infections ... Rhinosinusitis, CNS infection ... , Disseminated infection ... systemic vori Infectious ... #infectiousdiseases
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
infection (IFI) ... surfaces - Infections ... BAL GM does not differentiate ... Clav (may be + as long ... Sara Dong #Fungal
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
Pleural Effusion - Differential ... Superior vena cava ... Pneumonectomy • Trapped lung ... syndrome • Protein-losing ... Urinothorax Exudate - Infectious
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
associated with infection ... Cerumen impaction Infectious ... Caused by bacterial infections ... (90%), Fungal infections ... • Tumor • Infection
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
to Eosinophilic Lung ... , CNS, skin • Infectious ... (Variable) - Fungal ... #Diseases #pulmonary ... #differential #
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
component of many fungi ... surfaces, Albumin, Infections ... Spec 81% for dx ... in BAL does not differentiate ... result in + as long
Concurrent Brain and Lung Lesions
 • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
) • Fungi: Aspergillus ... Sara Dong @swinndong ... #Infections #Concurrent ... #Differential # ... Diagnosis #causes #infectiousdiseases
Concurrent Brain and Lung Lesions
 • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
) • Fungi: Aspergillus ... Sara Dong @swinndong ... #Infections #Concurrent ... #Differential # ... Diagnosis #causes #infectiousdiseases
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... Pseudomonas FUNGAL ... #Infections #HIV ... #AIDS #pulmonary ... diagnosis #infectiousdiseases