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diagnosis hematology aclf apml chronic cirrhosis differentiation failure hemophagocytic hlh leukostasis liver lymphohistiocytosis lysis oncology tls treatment tumor
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... EmoryGastroHep #ACLF #Acute ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... : • Common: fever ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... - 80% have fever ... - ACS, AKI, acute ... TLS #diagnosis #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... presents as an acute ... following: • Fever ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
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