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dermatology rheumatology differential clinical algorithm classification hsp palpable physicalexam schonlein canimorsus cryoglobulinemia cryoglobulins dermatologic foot glomerulonephritis granulomatosis hematology joint legs
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Normal Complement: IgA ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #differential #diagnosis
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis) 55 year old male on tuberculosis treatment
seen in Henoch ... (HSP, IgA Vasculitis ... #HSP #IgA #Vasculitis ... #clinical #photo ... #dermatology #skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... Differential Diagnosis ... • Henoch-Schönlein ... #dermatology #rash
Henoch Schonlein Leg Rash - Palpable Purpura Purpura: Low Platelets or Vasculitis? 45 years old, seen in our
Leg Rash - Palpable ... purpura (IgA), ... later confirmed by skin ... #Legs #Rash #clinical ... #photo #dermatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... • Henoch Schönlein ... Sarcoidosis • GPA ... #differential #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Diagnosis Framework ... purple, hemorrhagic skin ... • Ig A vasculitis ... - GPA - EGPA ... #Differential #Diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Diagnosis Algorithm ... infection - RMSF - Henoch ... Schonlein Purpura ... cryoglobulins • Skin
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often present • Henoch ... (IgA vasculitis ... tract, and often causes ... mucositis - Rash ... • ANCA (Dx: GPA
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Skin ulcers ... - GPA, EGPA, microscopic ... • IgA vasculitis ... (Henoch-Schönlein
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, mucositis • Rash ... MPO > PR3 60/ GPA ... often present) Henoch ... (IgA Vasculitis ... tract, and often causes
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