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diagnosis differential management erythematosus hematology vasculitis algorithm allergy antibiotics autoimmune chronic classification cll comparison druginduced leukemia lymphocytic macrophage mas myopathy
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... Sjögrens (15%) Skin ... Demyelinating syndromes ... #SLE #systemic
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... lupus erythematosus ... Petechial or purpuric rash ... [SLE], AOSD) • ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... : • Symptoms limited ... Chronic B-cell activation ... #Systemic #Lupus
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... NPSLE rare, Malar rash ... months to years) Systemic ... #table #rheumatology
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy Mild Reaction - Itching, Minor rash
(mild type IV HSR ... mucosal involvement, skin ... eosinophilia systemic ... symptoms syndrome ... there is a strong clinical
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... lupus erythematosus ... Symptoms (Sx) in ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Symptoms (SX) in ... , mucositis • Rash ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Agent Orange or Hep ... C Clinical Presentation ... with no early symptoms ... Hepatomegaly • Skin
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ), dermato-rheumatologic ... ) • Anti-Mi2 (skin ... : • Gottron rash ... • Conduction system
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