16 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #rashes #differential ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... 3rd Decade Skin ... permanent alopecia Differential ... : • Symptoms limited
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... NPSLE rare, Malar rash ... constitutional symptoms ... #table #rheumatology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... ), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
(mild type IV HSR ... mucosal involvement, skin ... eosinophilia systemic symptoms ... syndrome, Hemolytic ... there is a strong clinical
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... Petechial or purpuric rash ... SJIA], systemic lupus ... erythematosus [SLE ... #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
(Clinical Dx). ... Behcet disease) Differential ... Oral aphthae : SLE ... • Arthritis: SLE ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
mucositis - Rash ... such as systemic lupus ... Presentation - Systemic Symptoms ... vasculitis, and SLE ... #diagnosis #rheumatology