5 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... Dermatomyositis • Fever ... #AntiMDA5 #Dermatomyositis ... #dermatology #diagnosis
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... fraction < 20% Differential ... #management #treatment
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... , vital sign instability ... - New-onset fever ... sulfa-drug - Skin ... Targetoid #Algorithm #Differential
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
rash in association ... Fever >38.5 2. ... Resolution > 15 days Differentials ... withdrawal • Mild ... #management
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Anti-MDA5 (RP-ILD ... ) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... ) • Shawl sign