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dermatology disease hematology lupus stills treatment adultonset aosd blood dermatomyositis differential product reactions sle syndrome activation adult antimda5 antimda5dm antinxp2
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... • Rheumatic fever ... gangrenosum • IBD ... #differential #diagnosis ... #rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
with urticarial rash ... Rash: • Nonpruritic ... maculopapular skin ... #rheumatology # ... management
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
: High spiking fever ... maculopapular rash ... Systemic AOSD: high fever ... Disease #AOSD #rheumatology ... #diagnosis #management
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... Dermatomyositis • Fever ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
rash in association ... Fever >38.5 2. ... Skin involvement ... withdrawal • Mild ... #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Prognosis: Usually mild ... Lupusreference #druginduced ... comparison #table #rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... 3rd Decade Skin ... Differential Diagnosis ... to: Arthritis, Fever ... #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
- Nonremitting fever ... Petechial or purpuric rash ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... maculopapular rash ... infections with skin ... #Transfusion #diagnosis ... #management #hematology
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