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hematology management oncology chronic dermatology product reactions abdominal antimda5 antimda5dm causes cll dermatomyositis differential erythematosus fungal gastroenterology infections infectiousdiseases lupus
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... Lymphadenopathy • HSM • Fevers ... CLL -> Invade Skin ... #Hematology #Oncology ... #Diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... sudden onset of a rash ... - Rash: multiple ... cutis Diagnosis ... neutrophils in the blood
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Hepatomegaly • Skin ... Lymphocytosis: Absolute blood ... ’s lymphoma or acute ... #diagnosis #workup
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... Dermatomyositis • Fever ... onset [33-74%] • Blood ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... 3rd Decade Skin ... Classification: • Acute ... Hodgkin lymphoma and leukemia ... #Rheumatology
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
potentially be an acute ... Red Flags: • Fever ... the patient • Blood ... Back pain • Skin ... infarction • Lymphoma/Leukemia
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... maculopapular rash ... Transfusion Related Acute ... infections with skin ... #Transfusions #diagnosis
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... maculopapular rash ... Transfusion Related Acute ... infections with skin ... #Transfusion #diagnosis
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
respiratory symptoms • Fever ... pulmonary symptoms • Rheumatologic ... • Major blood ... Aspergillosis Pathophysiology ... have positive blood
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