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diagnosis rheumatology dermatology management neurology purpura vasculitis antimda5 antimda5dm antinxp2 antinxp2dm autoimmune capnocytophaga dm encephalitis erythematosus foot fulminans heat heatstroke
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... ulcerations • Skin ... auricular papules Clinical
Acute Purpura Fulminans Skin Rash on Physical Exam 60 year old male ITP s/p splenectomy 1d
Purpura Fulminans Skin ... Exam 60 year old ... rigors, diarrhea, nausea ... #Rash #clinical ... #photo
Moccasin-variety Tinea Pedis 70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Over the years: rash ... dermatophytes cause ... skin of inflamed ... Variety #type #clinical ... #photo #foot #dermatology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... Pathogenesis and clinical ... processes occur in the skin ... -> Heliotrope Rash ... Pathophysiology #Signs
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Heat Stroke - Differential ... fatigue Heat Rash ... blisters on the skin ... → Syncope • Signs ... Pale and sweaty skin
Henoch Schonlein Leg Rash - Palpable Purpura Purpura: Low Platelets or Vasculitis? 45 years old, seen in our
45 years old, seen ... Tip: To differentiate ... later confirmed by skin ... #clinical #photo ... #dermatology #HSP
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... Maculopapular rash ... • Common clinical ... Acute meningeal signs ... • Uveitis • Rash
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... auricular papules Clinical ... Muscle atrophy may cause ... : • ILD was diagnosed
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... permanent alopecia Differential ... Still disease, dermatomyositis ... and CNS • Headache
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... of shoulder and hip ... , mucositis • Rash ... tract, and often causes ... chorioretinitis, CNS
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