12 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... Inverse Gottron’s sign ... ulcerations • Skin
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
& hemorrhagic rash ... meningitis, orchitis & encephalitis ... that persists as skin ... Vesicular & pruritic rash ... degeneration -> Mild
Moccasin-variety Tinea Pedis 
70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Moccasin-variety Tinea ... Over the years: rash ... dermatophytes cause ... skin of inflamed ... type #clinical #photo
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
Purpura Fulminans Skin ... Exam 60 year old ... rigors, diarrhea, nausea ... Your blood cxs identify ... #photo
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... processes occur in the skin ... -> Heliotrope Rash ... dehydrogenase (LD ... Pathophysiology #Signs
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... Herpesviruses (MCC: HSV ... Maculopapular rash ... Acute meningeal signs ... • Uveitis • Rash
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
fatigue Heat Rash ... blisters on the skin ... → Syncope • Signs ... Pale and sweaty skin ... differential #diagnosis #causes
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs ... Causes: - Idiopathic ... multiforme - Dermatomyositis
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... Muscle atrophy may cause ... : • ILD was diagnosed
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Still disease, dermatomyositis ... and CNS • Headache ... , mild cognitive ... Cranial neuritis • Encephalitis