13 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... gangrenosum • IBD ... lesions • Discoid lupus ... #rashes #differential
Christmas Tree Rash of Pityriasis rosea
 - small oval scaling patches
 - Christmas tree pattern
 -
Christmas Tree Rash ... parallel to lines of skin ... palms/soles - Differential ... nummular eczema, tinea ... #dermatology #photo
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Prognosis: Usually mild ... Manifestations: Malar rash ... Usual therapeutic management ... rheumatology #diagnosis #management
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... Proliferative Class Ill ... #Nephritis #SLE ... Classification #Classes #differential ... #diagnosis #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin ... Treatment: • Mild ... #Systemic #Lupus ... #rheumatology #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... permanent alopecia Differential ... CNS • Headache, mild ... Seizures • Strokes Skin
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... arthritis - with the skin ... with Systemic Lupus ... Erythematosus (SLE ... like “butterfly rash
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin ... Rash - Differential ... Herald's atch • Tinea ... soles • Discoid Lupus ... #dermatology #Differential
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... rash in association ... Skin involvement ... Resolution > 15 days Differentials ... withdrawal • Mild
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... Petechial or purpuric rash ... SJIA], systemic lupus ... erythematosus [SLE ... Syndrome #Diagnosis #Management