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dermatology differential management dermatomyositis hematology product reactions vasculitis antimda5 antimda5dm antinxp2 antinxp2dm autoimmune classification common dermatologic distribution gpa granulomatosis myopathy
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... onset [33-74%] • Blood ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... lesions (9.4%) • Maculopapular ... rash (6.7%) • ... vasculitis (inflamed blood ... #diagnosis #rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs ... Causes: - Idiopathic ... neutrophils in the blood
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
associated with signs ... with site, (e.g„ tinea ... - Trunk - Red, blood-filled ... #dermatology #rash ... #differential #diagnosis
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
/sx urticaria, maculopapular ... rash, pruritis, ... infections with skin ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
/sx urticaria, maculopapular ... rash, pruritis, ... infections with skin ... #Transfusions #diagnosis ... #management #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... purpura: strong sign ... Large Vessel: Blood ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... pulses, bruits, or blood ... , mucositis • Rash ... tract, and often causes ... #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... Muscle atrophy may cause ... #management #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... ) • Shawl sign ... statins - probably caused
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