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dermatology differential dermatomyositis management vasculitis antimda5 antimda5dm antinxp2 antinxp2dm autoimmune classification dermatologic dress gpa granulomatosis myopathy myositis oncology polyangiitis sweet
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... lesions (9.4%) • Maculopapular ... rash (6.7%) • ... • Goodpasture syndrome ... #diagnosis #rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
rash in association ... • Maculopapular ... Edema in 70% of cases ... withdrawal • Mild ... SinaiBmoreIMRes #DRESS #Syndrome
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs ... general feeling of ill ... Causes: - Idiopathic
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... , mucositis • Rash ... tract, and often causes ... vesicles, pustules, maculopapular ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... tract, and often causes ... mucositis - Rash ... purpura: strong sign ... #rheumatology #
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... Muscle atrophy may cause ... Dermatomyositis: • ILD ... #management #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... ) • Shawl sign ... statins - probably caused
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