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dermatology differential dermatomyositis lupus sle systemic vasculitis antimda5 antimda5dm antinxp2 antinxp2dm autoimmune classification clinical dermatologic foot granulomatosis management moccasin myopathy
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Pain Rash ... Sarcoidosis • GPA ... Antiphospholipid-antibody syndrome ... #differential #diagnosis ... #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... surfaces of the joints ... Maculopapular rash ... • Goodpasture syndrome ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... signs #symptoms #diagnosis ... #rheumatology
Moccasin-variety Tinea Pedis 70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Over the years: rash ... Diagnosis? ... dermatophytes cause ... sp. pruritic, erythematous ... skin of inflamed
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... Arthritis: • Joint ... arthropathy • 90% joints ... #Diagnosis #Rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... rash on the face ... interphalangeal joints ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
> PR3 60% • GPA ... tract, and often causes ... vesicular eruption - Joints ... mucositis - Rash ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
: Erythematous nodules ... , mucositis • Rash ... MPO > PR3 60/ GPA ... tract, and often causes ... #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
rash on the face ... interphalangeal joints ... Muscle atrophy may cause ... Dermatomyositis: • ILD ... #management #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... : Fever, joint pain ... statins - probably caused
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