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dermatology differential dermatomyositis lupus systemic vasculitis antimda5 antimda5dm antinxp2 antinxp2dm autoimmune classification clinical dermatologic foot gpa granulomatosis hematology leukemia management
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Pain Rash ... Antiphospholipid-antibody syndrome ... #differential #diagnosis ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... #systemic #erythematosus ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... rash • Erythematous ... Differential Diagnosis ... Arthritis: • Joint ... #Diagnosis #Rheumatology
Moccasin-variety Tinea Pedis 70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Over the years: rash ... Diagnosis? ... dermatophytes cause ... sp. pruritic, erythematous ... skin of inflamed
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... rash on the face ... interphalangeal joints ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... surfaces of the joints ... Maculopapular rash ... • Goodpasture syndrome ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... vesicular eruption - Joints ... mucositis - Rash ... vasculitis, and SLE ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... : Erythematous nodules ... , mucositis • Rash ... tract, and often causes ... #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... bone pain, fever, joint ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Oncology #Diagnosis
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... rash on the face ... interphalangeal joints ... Muscle atrophy may cause ... #management #rheumatology
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