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diagnosis rheumatology vasculitis classification dermatology joint management activation algorithm arthropathies arthropathy capnocytophaga comparison cryoglobulinemia cryoglobulins disorders druginduced fulminans hand hematology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... gangrenosum • IBD ... lesions • Discoid lupus ... #rashes #differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... Sjögrens (15%) Skin ... , Vasculitis, Purpura ... #SLE #systemic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... rash • Erythematous ... permanent alopecia Differential ... lupus erythematosus ... #Systemic #Lupus
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
arthritis - with the skin ... Lupus - with Systemic ... Lupus Erythematosus ... (SLE), should have ... like “butterfly rash
Acute Purpura Fulminans Skin Rash on Physical Exam 60 year old male ITP s/p splenectomy 1d
Skin Rash on Physical ... Exam 60 year old ... shock, multiorgan system ... #Rash #clinical ... #photo
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... (Petechial or purpuric ... rash) • Heart, ... lupus erythematosus ... [SLE], AOSD) •
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Prognosis: Usually mild ... months to years) Systemic ... Lupus Erythematosus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... : erythematous nodules ... mucositis - Rash ... lupus erythematosus ... vasculitis, and SLE
Lymphocutaneous Sporotrichiosis Infection Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis? Lymphocutaneous
painless nodular rash ... trauma leads to skin ... Papulonodular, erythematous ... , painless, no systemic ... #photo #hand
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... - Skin ulcers ... Syndrome: • Clinical ... reticularis & skin ... lupus erythematosus
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