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rheumatology differential dermatology vasculitis classification sle systemic activation cryoglobulinemia cryoglobulins dermatologic dermatoses dermatosis gpa granulomatosis hematology joint macrophage management mas
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... Crohn's disease Palpable ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #differential #diagnosis
Pigmented Purpuric Dermatoses (PPD) - Capillaritis Group of chronic, benign, cutaneous eruptions characterized by the presence of
and increased skin ... brown tint of the rash ... lesions and erythematous ... eczematous features • Mild ... #differential #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
• Petechiae, Palpable ... Maculopapular rash ... • Petechiae • Palpable ... • Goodpasture syndrome ... #dermatology #rash
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... signs #symptoms #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... CNS • Headache, mild ... Seizures • Strokes Skin ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
and/or pulmonary capillaritis ... : erythematous nodules ... mucositis - Rash ... erythematosus, ... -> causing palpable
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... rash) • Heart, ... SJIA], systemic lupus ... erythematosus [ ... #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
: Erythematous nodules ... , mucositis • Rash ... ) • Pulmonary capillaritis ... , palpable purpura ... ) • Palpable purpura
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... Clinical triad of Palpable ... Labs/Diagnosis: ... (e.g. systemic lupus ... erythematosus (
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