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diagnosis rheumatology differential dermatology classification sle activation algorithm alopecia arthropathies arthropathy autoimmune clinical cryoglobulinemia cryoglobulins dermatitis dermatologic disorders erythema gpa
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Pain Rash ... gangrenosum • IBD ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... , Vasculitis, Purpura ... Demyelinating syndromes ... #erythematosus # ... signs #symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: erythematous nodules ... vesicular eruption - Joints ... mucositis - Rash ... lupus erythematosus ... : strong sign of
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Lupus - with Systemic ... Lupus Erythematosus ... like “butterfly rash
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Arthritis: • Joint ... lupus erythematosus ... #Lupus #Erythematosus
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
surfaces of the joints ... Maculopapular rash ... macules • Erythematous ... • Goodpasture syndrome ... #dermatology #rash
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis) 55 year old male on tuberculosis treatment
(HSP, IgA Vasculitis ... ) 55 year old ... abdominal pain, joint ... #clinical #photo ... #dermatology #skin
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
: Strong sign of ... : Erythematous nodules ... vesicular eruption • Joints ... , mucositis • Rash ... , joint & gut involvement
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... easy bruising to purpura ... (Petechial or purpuric ... rash) • Heart, ... lupus erythematosus
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... - Skin ulcers ... reticularis & skin ... disorder (e.g. systemic ... lupus erythematosus
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