9 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Aseptic necrosis of hip ... signs #symptoms #diagnosis ... #rheumatology
Moccasin-variety Tinea Pedis 
70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Moccasin-variety Tinea ... Over the years: rash ... Diagnosis? ... skin of inflamed ... type #clinical #photo
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Seizures • Strokes Skin ... #Rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can activate ... - Purpura - Skin ... Labs/Diagnosis: ... (e.g. systemic lupus ... classification #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... WAIHA • CAD • PCH ... • Lupus anticoagulant ... #Differential #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Schonlein Purpura (IgA ... inflammation Others: • Lupus ... mucositis - Rash ... such as systemic lupus ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
of shoulder and hip ... , mucositis • Rash ... Schonlein Purpura (IgA ... , IgA (cmpkx deposits ... #Rheumatology
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
Characteristic Rash ... • Sexual activity ... Umbilification - Rash ... chain reaction (PCR ... Monkeypox #MPOX #Diagnosis
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... ) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... weakness + atrophy- Hip ... Other Diseases: • PBC