13 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Manifestations: Malar rash ... Positive in 60-80% of cases ... - pANCA anti-MPO ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... - ANA > 95% (IgG ... - pANCA anti-MPO ... Discontinuation of causal ... #diagnosis #management
Moccasin-variety Tinea Pedis 
70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Over the years: rash ... Diagnosis? ... dermatophytes cause ... skin of inflamed ... type #clinical #photo
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
disease that is caused ... Characteristic Rash ... chain reaction (PCR ... #Diagnosis #Management ... #Dermatology
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin ... Rash - Differential ... Herald's atch • Tinea ... soles • Discoid Lupus ... #Algorithm #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Schonlein Purpura (IgA ... tract, and often causes ... mucositis - Rash ... such as systemic lupus ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
of shoulder and hip ... , mucositis • Rash ... tract, and often causes ... , IgA (cmpkx deposits ... #Rheumatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
NPSLE rare, Malar rash ... - pANCA anti-MPO ... Discontinuation of causal ... #diagnosis #treatment ... #management
Rickettsialpox Eschar

40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis?
Rickettsialpox R akari classic
Diagnosis? ... Dx: serology; pcr ... chickenpox, vzv, hsv ... rakari #clinical #photo ... #skinrash #dermatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... recipients w/ IgA ... infections with skin ... #Transfusion #diagnosis ... #management #hematology