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diagnosis rheumatology differential vasculitis classification dermatology sle systemic algorithm arthropathies arthropathy cryoglobulinemia dermatologic disorders gpa granulomatosis monoarthritis monoarticular msk pain
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Pain Rash ... infection Malar rash ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... reticularis & skin ... arthralgia, and arthritis ... (e.g. systemic lupus ... erythematosus (
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- (Reiter’s syndrome ... - with the skin ... with Systemic Lupus ... Erythematosus ( ... like “butterfly rash
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... of hip (rare), Arthritis ... Demyelinating syndromes
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Joint pain • Swan ... arthropathy • 90% joints ... Antiribosomal P, APLA, PAC ... Seizures • Strokes Skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
surfaces of the joints ... Maculopapular rash ... • Goodpasture syndrome ... • Giant cell arteritis ... #dermatology #rash
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: erythematous nodules ... vesicular eruption - Joints ... mucositis - Rash ... erythematosus, ... Serologies for Cryoglobulins
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
: Erythematous nodules ... vesicular eruption • Joints ... , mucositis • Rash ... , joint & gut involvement ... vasculitis • Cogan syndrome
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