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diagnosis differential vasculitis classification dermatology systemic activation algorithm arthropathies arthropathy cryoglobulinemia cryoglobulins dermatologic disorders gpa granulomatosis hematology macrophage management mas
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Pain Rash ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... #erythematosus #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... rash • Erythematous ... Arthritis: • Joint ... arthropathy • 90% joints
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Erythematosus ( ... SLE), should have ... like “butterfly rash
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
surfaces of the joints ... Maculopapular rash ... • Goodpasture syndrome ... #dermatology #rash ... #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... rash) • Heart, ... erythematosus [ ... SLE], AOSD) • Infection ... #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... (e.g. systemic lupus ... erythematosus ( ... SLE), rheumatoid ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... mucositis - Rash ... erythematosus, ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... : Erythematous nodules ... , mucositis • Rash ... , joint & gut involvement ... Differential #Diagnosis #Rheumatology
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