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differential dermatology rheumatology algorithm clinical hematology causes classification signs symptoms alopecia disorders hairloss hand joint lupus management oncology pathophysiology primary
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... Antiphospholipid-antibody syndrome ... • Vasculitis ... #differential #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... macules • Erythematous ... Differential Diagnosis ... • Goodpasture syndrome ... #dermatology #rash
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
systemic lupus erythematosus ... - purpura-arthralgia-nephritis ... syndrome induced ... #Vessels #Diagnosis ... #Rheumatology #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... : erythematous nodules ... mucositis - Rash ... • Cogan Syndrome ... systemic lupus erythematosus
Small Vessel Vasculitides • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Interstitial lung disease ... systemic lupus erythematosus ... and Sjogren's syndrome ... in absence of skin ... #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Diagnosis Framework ... purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #Differential #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... : Erythematous nodules ... , mucositis • Rash ... • Cogan syndrome
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... Antiribosomal P, APLA, PAC ... Seizures • Strokes Skin ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... pain (20%) Renal disease
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Diagnosis Framework ... Petechiae, Palpable purpura ... : • Behcet Disease ... • Cogan syndrome ... #differential #diagnosis
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