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diagnosis rheumatology differential vasculitis dermatology erythematosus lupus signs symptoms systemic brain causes classification cns cutaneous joint lesions management neurology pain
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... Palpable purpura ... Henoch Schönlein purpura ... Antiphospholipid-antibody syndrome
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
lesions, palpable purpura ... response to local skin ... test (this is a skin ... Oral aphthae : SLE ... • Arthritis: SLE
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Secondary: CTD: SLE ... Petechiae, Palpable purpura ... Vasculitis: • Behcet ... Disease • Cogan ... syndrome #Cutaneous
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... pain (20%) Renal disease
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
Diagnosis- Compatible syndrome ... toxo IgG • CNS PCR ... nodules, may also see ... skin lesions, LAD ... Sarcoidosis • Neuro Behcets
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... VASCULITIS: • Behçet ... Syndrome: - Recurrent ... • Cogan Syndrome ... vasculitis, and SLE
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... , mucositis • Rash ... vasculitis • Behcet ... syndrome: Recurrent ... vasculitis • Cogan syndrome
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... 3rd Decade Skin ... Photosensitive rash ... Antiribosomal P, APLA, PAC ... Seizures • Strokes Skin
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