9 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... Rash • Human ... infection Malar rash ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... lesions Abdominal pain
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
lesions • Severe pain ... : - Purpura fulminans ... Autoimmune Vasculitis (lupus ... cryoglobulins • Skin ... #dermatology #physicalexam
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Arthritis: • Joint pain ... Antiribosomal P, APLA, PAC ... Seizures • Strokes Skin
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
now abdominal pain ... , joint pain involving ... Vasculitis #clinical #photo ... #dermatology #skin ... #rash #physicalexam
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... mucositis - Rash ... such as systemic lupus ... , testes -> pain ... vasculitis, and SLE
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... • Fever is the main ... rash) • Heart, ... SJIA], systemic lupus ... erythematosus [SLE
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
lesions, palpable purpura ... response to local skin ... Oral aphthae : SLE ... • Arthritis: SLE ... Nonsurgical abdominal pain
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... tract: Abdominal pain ... , mucositis • Rash ... involvement, abdominal pain ... vasculitis • Cogan syndrome