9 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Antiphospholipid-antibody syndrome ... • Vasculitis ... lesions • Discoid lupus
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... mucositis - Rash ... • Cogan Syndrome ... such as systemic lupus ... , and SLE) • Urinalysis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... diseases: - 10% SLE ... reticularis & skin ... (e.g. systemic lupus ... erythematosus (SLE
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Infection - Vasculitis ... : - Purpura fulminans ... (lupus, RA, Sjogren's ... cryoglobulins • Skin ... #dermatology #physicalexam
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... ANCA-associated vasculitis ... Antiribosomal P, APLA, PAC ... Seizures • Strokes Skin
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
(HSP, IgA Vasculitis ... ankles and palpable rash ... #clinical #photo ... #dermatology #skin ... #rash #physicalexam
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... Mucocutaneous lymph node syndrome ... , mucositis • Rash ... • Behcet syndrome ... • Cogan syndrome
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... lesions, palpable purpura ... vessel vasculitis ... Oral aphthae : SLE ... • Arthritis: SLE