11 results
diagnosis pediatrics physicalexam clinical genetics growthhormone newborn pituitary symptoms 21hydroxylasedeficiency 21ohd brudzinskis comatose differential embolism examination excess fat feedbackloop glftap
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... Incr IGF1 • Bone ... activates lipolysis Signs ... #FeedbackLoop #endocrinology ... #pathophysiology
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski) Brudzinski's sign is characterized
Brudzinski’s Sign ... Brudzinski's sign ... Passive neck flexion causes ... While the pathophysiology ... PhysicalExam #Pediatrics #Peds
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 Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Signs/Symptoms ... Infertility • Decr Bone ... #genetics #pathophysiology ... #peds #pediatrics
Fat Embolism Syndrome Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Fat Embolism Syndrome ... Trauma to the long bone ... accounts for —9096 of cases ... Pathophysiology ... #Diagnosis #Signs
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
For pituitary masses ... following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
evaluation should be done ... hypertension and signs ... renal bruit or signs ... Vasculitis • Endocrinologic ... White-coat syndrome
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Newborn Infant - Routine Examination Birthweight, gestational age and birthweight percentile are noted. General observation Of the baby's
is also a late sign ... are observed for signs ... intra-abdominal masses ... Muscle tone is assessed ... #Examination #Peds
Tone - Hand Position on Physical Exam A newborn baby’s hand is held in a fisted position
Tone - Hand Position ... hand will often cause ... fisted hand is a sign ... PhysicalExam #clinical #video ... #peds #pediatrics
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