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Hyperthermic Syndromes - This table summarizes the similarities and differences between some toxicologic causes of hyperthermic
Hyperthermic Syndromes ... Antimuscarinic toxidrome ... Sympathomimetic toxidrome ... • Malignant Hyperthermia ... #Syndromes #Comparison
The Hot and Altered Patient in the ED - Differential Diagnosis Framework
 • Heat Stroke
 •
Storm • Malignant Hyperthermia ... Sympathomimetic Toxidrome ... Anticholinergic Toxidrome ... SarahFoohey #Hot #fever ... Differential #Diagnosis #delirium
Toxidromes: Serotonin Syndrome, Neuroleptic Malignant Syndrome, Anticholinergic Delirium - Venn Diagram

All: Hypertension, Tachycardia

Anticholinergic Delirium:
- dilated pupils,
Toxidromes: Serotonin ... Anticholinergic Delirium ... Anticholinergic Delirium ... psypharmacopeia #Toxidromes ... Anticholinergic #Comparison
Management Algorithm for Confusion
- Substrate verification, glucose, oxygen checks
- Toxidrome present
- Focal findings on neurologic examination
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oxygen checks - Toxidrome ... examination - Fever ... AlteredMentalStatus #Delirium
Hyperthermic Toxidromes
Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures.
 • Sympathomimetic -
Hyperthermic Toxidromes ... Five toxidromes ... overlapping features: hyperthermia ... ) • Malignant Hyperthermia ... #Toxidromes #comparison
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
CNS: Agitation, Delirium ... : Tachycardia, Fever ... Hypertonicity, Hyperthermia
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Fever vs Hyperthermia ... Fever: • Regulated ... BrighamChiefs #Fever ... #Hyperthermia # ... comparison #diagnosis