224 results
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
Tranexamic Acid: ... Mechanism of Action - TXA ... anti-fibrinolytic - TXA ... acid lysine - TXA ... fibrin-rich clot #Tranexamic
Multiple Uses for Tranexamic Acid (TXA) - Evidence Based Indications and Dosing

Trauma < 3 hrs •
Multiple Uses for Tranexamic ... Acid (TXA) - Evidence ... Hemoptysis YES #TXA
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid ... disturbances #TXA ... #Tranexamic #Acid
The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an
Antifibrinolytic Trial): tranexamic ... controlled trial - Tranexamic ... consider giving tranexamic ... Obgyn #WOMANTrial #TXA
SGEM#210: (Don’t) Let it Bleed – TXA for Epistaxis in Patients on Anti-Platelet Drugs. Zahed et
Let it Bleed – TXA ... Topical Tranexamic ... KirstyChallen #EBM #TXA
Pediatric Trauma Primary Survey: C-ABCDE
C - Catastrophic Bleeding - Life-threatening hemorrhage
 • Apply direct pressure/compression bandage
Consider qivinq tranexamic ... acid (TXA) as a ... Do NOT give TXA
Management of Anaphylaxis - Interventions
Epinephrine - Bolus, Infusion, Nebulized
Posture
O2
Fluids
Albuterol 
H1-Antihistamines, H2-Antihistamines
Glucocorticoids
Additional Vasopressor
Glucagon
Sugammadex
Methylene blue
Tranexamic acid
ECMO

#anaphylaxis #management #treatment
Methylene blue Tranexamic
Woman – The TXA Trial for Post-Partum Hemorrhage.  Lancet. 2017 May 27
https://www.ncbi.nlm.nih.gov/pubmed/28456509

#EBM #OBGyn #WOMANTrial #TXA
Woman – The TXA ... OBGyn #WOMANTrial #TXA
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
increased -> 1000mg tranexamic
Thromboelastography (TEG) Based Management
 - If R time prolonged -> FFP 
 - If MA low
increased -> 1000mg tranexamic