25 results
Causes of Purpura - Differential Diagnosis
Disruption in Vascular Integrity: 
 • Trauma, Infection, Vasculitis, Drug induced
Causes of Purpura - Differential ... Integrity: • Trauma ... Primary hemostasis: Thrombocytopenia ... , Platelet dysfunction ... BrighamChiefs #Purpura #nonpalpable
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
with devastating differential ... presents in thrombocytopenic ... palpable, the differential ... #Diagnosis #Dermatology ... #Differential
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... chain IIA • Thrombocytopenia ... fibrinogen) • Thrombocytopenia ... comparison #table #differential ... #diagnosis #hematology
Causes of Thrombocytopenia.
Platelet counts may be depressed because of decreased production or due to increased platelet
Causes of Thrombocytopenia ... Platelet counts ... #Diagnosis #Hematology ... #Thrombocytopenia ... #Differential #
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... Diagnosis Platelet ... rheumatologic, trauma ... Thrombocytosis #Differential ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... Solar purpura - Trauma ... rheumatology #palpable #nonpalpable ... #dermatology
PLATELETS Mnemonic for Causes of Thrombocytopenia

P - Platelet Disorders (DIC, ITP, TTP)
L - Leukemia, Lymphoma
A -
for Causes of Thrombocytopenia ... Aplastic Anemia T - Trauma ... Mnemonic #Acronym #Thrombocytopenia ... #Differential # ... Diagnosis #Hematology
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia ... - Differential ... #Differential # ... Diagnosis #Algorithm #hematology ... #platelets
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... 1 or Type 3) — differentiate ... Gplb receptor • Thrombcytopenia ... #disorders #hematology ... #hemepath #differential
Causes of Purpura - Differential Diagnosis
Non-PalpabIe → Palpable
 • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura - Differential ... → Palpable • Thrombocytopenia ... warfarin necrosis), Trauma ... BrighamChiefs #Purpura #nonpalpable ... palpable #Causes #Differential