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hematology differential algorithm management clinical thrombocytopenia causes platelet anemia purpura treatment workup coagulation comparison disorders skinrash teg thromboelastography bleeding hemolytic
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
- Differential Diagnosis ... Platelet Count ... Non-infectious (malignancy, rheumatologic ... , trauma) • Post-splenectomy ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... Inflammatory Conditions: Rheumatologic ... infarction, Severe trauma ... #Algorithm #hematology
Idiopathic Thrombocytopenic Purpura Clinical: • Gingival • Menorrhagia • GI bleeding • Intracranial
children) • Platelets ... extremely low platelet ... Thrombocytopenia #Diagnosis ... #Overview #Hematology
Thromboelastography (TEG) Based Management - If R time prolonged -> FFP - If MA low
cryoprecipitate - If platelets ... < 50 -> platelet ... Management #treatment #diagnosis ... #hematology
Thromboelastography (TEG) based therapy and Management If r time prolonged -> FFP If MA low -> plts/cryoprecipitate (if
cryoprecipitate If platelets ... < 50 - > platelet ... TEG #Management #Diagnosis ... #Hematology #Thromboelastogram
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... #differential #diagnosis ... #hematology
Causes of Acquired Platelet Dysfunction #Acquired #Platelet #Dysfunction #Causes #differential #Diagnosis #hematology
Causes of Acquired Platelet ... #Acquired #Platelet ... #differential #Diagnosis ... #hematology
Causes of Thrombocytopenia. Platelet counts may be depressed because of decreased production or due to increased platelet
Platelet counts ... due to increased platelet ... #Diagnosis #Hematology
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 Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... count and platelet ... • Platelet flow ... #disorders #hematology ... #differential #diagnosis
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
Purpura (TTP) Diagnosis ... secondary TMA), Platelets ... soon as TTP is diagnosed ... management #treatment #rheumatology ... #hematology
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