29 results
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Idiopathic Thrombocytopenic ... children) • Platelets ... extremely low platelet ... #Diagnosis #Overview ... #Hematology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Platelet Count ... Non-infectious (malignancy, rheumatologic ... , trauma) • Post-splenectomy ... #causes #Platelets ... #hematology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... , Large platelets ... without platelet ... #differential #diagnosis ... #hematology
PLATELETS Mnemonic for Causes of Thrombocytopenia

P - Platelet Disorders (DIC, ITP, TTP)
L - Leukemia, Lymphoma
A -
PLATELETS Mnemonic ... P - Platelet ... Aplastic Anemia T - Trauma ... S - Sepsis #PLATELETS ... #Hematology
Causes of Thrombocytopenia.
Platelet counts may be depressed because of decreased production or due to increased platelet
Causes of Thrombocytopenia ... Platelet counts ... due to increased platelet ... #Diagnosis #Hematology ... #Thrombocytopenia
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... count and platelet ... Gplb receptor • Thrombcytopenia ... #disorders #hematology ... #differential #diagnosis
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Heparin-Induced Thrombocytopenia ... (platelet count ... Timing of onset of platelet ... #HIT #hematology ... #diagnosis #4Ts
Algorithm for diagnosis of familial thrombocytopenia. Platelet size, best determined by review of the peripheral smear,
Algorithm for diagnosis ... of familial thrombocytopenia ... Platelet size, best ... #Diagnosis #Hematology ... #Familial #Thrombocytopenia
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia ... - Differential Diagnosis ... #Differential #Diagnosis ... #Algorithm #hematology ... #platelets
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... → Refer to hematology ... infarction, Severe trauma ... Thrombocytosis #Platelets ... #Algorithm #hematology