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hematology leukemia management apml calcium chronic cll comparison deposition differentiation disease gout lymphocytic pseudogout pyrophosphate workup
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
Acute CPP Crystal ... • Metabolic syndrome ... 12-24 Hours • Fever ... Gout #Comparison #rheumatology ... #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... : • Common: fever ... Differentiation #Syndrome ... #management #hematology ... #oncology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Acute CPP Crystal ... culture used to diagnose ... Crowned Dens Syndrome ... neck pain, fever ... Deposition #Disease #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Lymphadenopathy • HSM • Fevers ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... • Richter’s Syndrome ... ’s lymphoma or acute ... #workup #oncology ... #hematology
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