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C. Difficile Infection in IBD - IBD Algorithm

Background
Complications
CDI Testing Algorithm
CDI Recurrence

Dr. Wade Billings @wabillin

#Clostridioides #difficile #CDiff
- IBD Algorithm ... Complications CDI ... Clostridioides #difficile #CDiff ... #Algorithm #Management ... #Treatment #Gastroenterology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Epidemiology: • #1 ... 10 mg/kg IV x 1 ... Treatment Guideline ... #Cdiff #Clostridioides ... #IDSA #gastroenterology
Inflammatory Bowel Disease (IBD) - Inpatient Management Checklist
History and physical examination
 - Assess for disease severity
Bowel Disease (IBD ... Checklist History ... Radiographic evaluation Medication ... #treatment #Checklist ... #gastroenterology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Failure, Toxins/Medications ... Goals: 1) MAP ... 3) UOP > 0.5 cc ... Differential #Diagnosis #criticalcare ... #management
IBD Colonoscopy Surveillance 
LOW RISK - Follow-up Colonoscopy at 3 years:
 • Quiescent disease , Endoscopic
IBD Colonoscopy ... Colonoscopy at 1- ... Colonoscopy at 1 ... #Surveillance #Guidelines ... #management #gastroenterology
Perioperative IBD Pharmacotherapy Management 
Immunomodulators:
 • Stop MTX one week prior to elective surgery
 • Stop
Perioperative IBD ... Pharmacotherapy Management ... resume post op day 1 ... • Resume in CD ... Pharmacotherapy #medication
Ulcerative Proctitis
Proctitis:
 • Affects 1/3 patients
 • Predictors of extension:
     - Disease
Infection (CMV, c-Diff ... rectal prolapse, CD ... , cancer Treatment ... Ulcerative #Proctitis #IBD ... #diagnosis #management
Severe Influenza Checklist

Diagnostic tests 
 - Blood cultures x2 
 - Sputum gram stain & culture
Severe Influenza Checklist ... DO NOT bolus 30 cc ... 600 mg PO/IV q 1 ... suspected Adiunctive treatments ... #Management #CriticalCare
IDSA Recommendations for Prevention and Treatment of Pneumocystis Pneumonia (PCP) in HIV-AIDS
Indications for Initiating Primary Prophylaxis:
Prevention and Treatment ... ) in HIV-AIDS Indications ... daily or 50 mg PO BID ... IDSA #Prevention #Treatment ... infections #HIVAIDS #management
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS
Preventing CMV Disease:
 • CMV end-organ disease is best
ART to maintain CD4 ... ., concomitant medications ... injection) for 1– ... Valganciclovir 900 mg PO BID ... #management #opportunistic