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diagnosis hematology differential oncology antiphospholipid apls disorders eosinophil eosinophilia globulin leukemia mds myelodysplasia myelodysplastic nonpalpable palpable petechiae petechial physicalexam polycythemia
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... 1,500 cells/µL Workup ... for secondary causes ... symptoms (eg, skin
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... disease (VWD) • Hypercoagulable ... vasculitis - GPA ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... RA, Sjogren's, GPA ... deficiency Work ... cryoglobulins • Skin ... #Causes #dermatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Causes of Monoclonal ... gammopathy, and skin ... amyloidosis Causes ... • Hematology:
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... an underlying cause ... about secondary causes ... you’ll do a good workup ... #workup #hematology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
APLS) Testing - Hypercoagulable ... Workup Algorithm ... maternal chromosomal causes ... #Workup #Algorithm ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... or functional neutropenia ... CLL -> Invade Skin ... #Leukemia #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... just beneath the skin ... Myeloproliferative Disease • Neutropenia ... Workup: • Complete
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