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differential management rheumatology causes dermatology algorithm treatment liver anemia monoclonal vasculitis chronic cirrhosis classification hepatitis leukemia mgus myelodysplastic pathophysiology rash
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
- Differential Diagnosis ... breast CA, small cell ... Metabolic: Wilson Disease ... • Vascular: Budd-chiari ... #causes #hepatology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
ULN R - Renal disease ... diseases, CML, ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Diagnosis: • ... cells can indicate disease ... #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
• Clinical features ... Differential Diagnosis ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Allogeneic stem cell ... Myelodysplastic #Syndrome ... Management #treatment #hematology ... #oncology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #Differential #Diagnosis ... #hematology #rheumatology
Causes of Pleural Effusion - Differential Diagnosis Algorithm Transudate - Hydrostatic • Congestive heart failure • Constrictive
- Differential Diagnosis ... embolism • Collagen vascular ... disease • Gastrointestinal ... disease • Hemothorax ... #Algorithm #Hepatology
Causes of Portal Hypertension According to Site of Vascular Obstruction 1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
According to Site of Vascular ... Veno-occlusive disease ... post-sinusoidal: Budd-Chiari syndrome ... #differential #diagnosis ... #causes #hepatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... ) (e.g. lupus, CLL ... #hematology #anemia
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