14 results
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... Smoking, Microbial triggers ... #Cirrhosis #Pathophysiology ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Cholangitis • Abscess ... Cholangitis • Primary Biliary ... Cirrhosis #Hepatomegaly ... Diagnosis #Algorithm #Causes ... #Hepatology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Etiologies of Cirrhosis ... congenital - Primary biliary ... #Diagnosis #Differential ... #Hepatology #Cirrhosis ... #Causes
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... on Ultrasound Biliary ... Gallstones • Biliary ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
hepatitis, hepatic cirrhosis ... cirrhosis, sepsis ... miscellaneous causes ... #unconjugated #differential ... #causes
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... pregnancy • Primary biliary ... #Hypertension #Differential ... #Diagnosis #causes ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... intralobular bile ducts causes ... bile ducts Differential ... diagnosis #workup #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Infiltrative • Cirrhosis ... Duct Stone • Biliary ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Causes of Ascites ... - Differential ... - Hepatic: • Cirrhosis ... failure • Primary biliary ... Diagnosis #Algorithm #Hepatology
Etiology and Complications of Cirrhosis

#Causes #Complications #Cirrhosis #Differential #Pathophysiology #Hepatology
Complications of Cirrhosis ... #Causes #Complications ... #Cirrhosis #Differential ... #Pathophysiology ... #Hepatology