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diagnosis algorithm causes albumin cirrhosis gradient liver management pbc pediatrics primary saag workup abscess aflp apml bilirubinemia children cholangitis congenital
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
Diagnosis of ascites ... SAAG ≥ 1.1: - Ascitic ... syndrome SAAG < 1.1: Biliary ... albumin #gradient #hepatology ... #differential #
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Ascites - Differential ... Failure, Pancreatic, Biliary ... Chylous <1% #Ascites ... #Differential # ... Diagnosis #hepatology
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... Smoking, Microbial triggers ... #PBC #Primary #Biliary ... #hepatology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... on Ultrasound Biliary ... Gallstones • Biliary ... #Jaundice #Differential ... Algorithm #Causes #Hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... - Differential ... failure • Primary biliary ... #Differential # ... Diagnosis #Algorithm #Hepatology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
Approach and Differential ... Cell count and differential ... concentration (bowel or biliary ... #workup #Differential ... #Diagnosis #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... of portal HTN: ascites ... portal HTN: • Ascites ... pregnancy • Primary biliary ... Diagnosis #causes #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... develops (DIC, ascites ... infiltration) Differential ... Liver #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... No extrahepatic biliary ... bile ducts Differential ... diagnosis #workup #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Serum Ascites Albumin ... Gradient (SAAG) - Differential ... Tuberculosis - Biliary ... Albumin #Gradient #Differential ... #Diagnosis #hepatology
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