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diagnosis algorithm transaminitis hematology abnormal biliary causes injury primary syndrome workup apml calling chemistry cholangitis comparison consultation differentiation disorders elevated
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Primary Biliary Cirrhosis ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... • NAFLD • Cirrhosis ... #Differential # ... Diagnosis #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Ducts - PBC ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary Cirrhosis ... Smoking, Microbial triggers ... relative with PBC ... Cholestasis #PBC ... #hepatology
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
Gl History - Cirrhosis ... - Vitals - LFTs ... biopsy Meds: ... - Outpatient meds ... Calling #Referral #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Infiltrative • Cirrhosis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... /Liver failure ... or higher • Liver ... bile ducts Differential ... diagnosis #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... stone, Malignancy, PBC ... hepatitis: < 1 • Cirrhosis ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... hepatitis: < 1 • Cirrhosis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
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