14 results
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... inborn errors of metabolism ... Diagnosis #Algorithm #Differential ... #Neonatology #Peds ... Table #IEM #NICU #InbornErrors
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
Inborn Errors of Metabolism ... diagnosing acute metabolic ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... #InbornErrors ... #Peds #Pediatrics
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathies - Primary ... Drug-induced TMA - Metabolism-mediated ... Microangiopathies #Primary ... Microangiopathy #TMA #hematology ... #differential #
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... Smoking, Microbial triggers ... Cholestasis #PBC #Primary ... #hepatology
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Gilbert's Syndrome • Crigler-Najjar ... Cholangiocarcinoma • Primary ... #Jaundice #Differential ... Algorithm #Causes #Hepatology
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
Hyperammonemia - Differential ... Diagnosis Framework Hematologic ... Y t amino acid metabolism ... hyper-NH3 if elderly + urinary ... #Diagnosis #Pathophysiology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... Intermediate fatty acid metabolism ... infiltration) Differential ... Liver #Pregnancy #hepatology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
and decreased metabolism ... Reye syndrome (Peds ... ) - Primary carnitine ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
and Bilirubin Metabolism ... CAST) • ALT: primarily ... insult Bilirubin metabolism ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... bile ducts Differential ... malignancy #Primary ... diagnosis #workup #hepatology