19 results
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Environmental triggers ... - Postulate 1 ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... WBC >100k, + lab signs ... into serum • Triggers ... TLS #diagnosis #management
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... : 1. ... glucorticoids if 1)
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Diagnosis and Management ... endemic areas - 1- ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
The underlying pathophysiology ... mechanism exist): 1) ... Can be triggered ... Crisis #Features #Signs
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... • Prevalence: 1- ... associated with DM-1, ... Person Syndrome Pathophysiology ... tendency to fall • Triggers
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
of more of the signs ... repeat sample at 1- ... re-administration of possible trigger ... #Anaphylaxis #Anesthesiology ... Checklist #Diagnosis #Management
Hypothermia in Anesthesiology - Avoiding Hypothermia and Physiologic Changes with Hypothermia

Avoiding hypothermia: 

1. temperature in OR
Hypothermia in Anesthesiology ... hypothermia: 1. ... #Hypothermia #Anesthesiology ... #Pathophysiology ... #Physiologic #Management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
anaphylaxis (→ 3-1) ... hyperthermia crisis (late sign ... Differential #Causes #Anesthesiology ... Checklist #Diagnosis #Management
Local Anaesthetic Toxicity - Guidelines for Crises in Anaesthesia
Signs of severe toxicity:
 • Sudden alteration in
in Anaesthesia Signs ... Recovery may take >1 ... Anaesthetic #Toxicity #Anesthesiology ... Checklist #Diagnosis #Management