26 results
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Environmental triggers ... - Postulate 1 ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... WBC >100k, + lab signs ... into serum • Triggers ... TLS #diagnosis #management
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... : 1. ... glucorticoids if 1)
Scapholunate Dissociation
The spacing between all carpal bones should be 1-2 mm, look for the "Terry Thomas"
"Terry Thomas" sign ... ("Terry Thomas sign ... dislocation • ED Management ... XRay #Diagnosis #Management ... Orthopedics #Sports #MSK
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
distribution of nearly 3:1 ... • Lhermitte’s sign ... combination of: 1. ... Signs and symptoms ... sclerosis #diagnosis #management
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Diagnosis and Management ... endemic areas - 1- ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology
Triquetral Fracture
The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
"pooping duck sign ... "pooping duck sign ... fractures • ED Management ... follow-up within 1 ... Orthopedics #Sports #MSK
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
The underlying pathophysiology ... mechanism exist): 1) ... Can be triggered ... Crisis #Features #Signs
Supracondylar Elbow Fracture
• Most common elbow fracture in children, peak age 5-7 
• When looking at
anterior sail sign ... capitellum (age 1) ... can't make A-OK sign ... follow-up within 1 ... #Orthopedics #MSK
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... • Prevalence: 1- ... associated with DM-1, ... Person Syndrome Pathophysiology ... tendency to fall • Triggers