15 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... the study) • Triggers ... ATRA treatment Pathophysiology ... symptoms, or> 1 ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... WBC >100k, + lab signs ... into serum • Triggers ... #diagnosis #management
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
endemic areas - 1- ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... should be done in ALL
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... involves: (1) ... of UMN and LMN signs ... likelihood of this 1. ... neurology #diagnosis #management
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
of more of the signs ... repeat sample at 1- ... re-administration of possible trigger ... Intraoperative #Checklist ... #Diagnosis #Management
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... erythropoietin 1/ ... present, symptoms, signs ... transformation into AML ... PV #Diagnosis #Management
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Perforation) Pathophysiology ... Epidemiology: • #1 ... - produced by all ... 10 mg/kg IV x 1 ... #treatment #infectiousdiseases
Local Anaesthetic Toxicity - Guidelines for Crises in Anaesthesia
Signs of severe toxicity:
 • Sudden alteration in
in Anaesthesia Signs ... tachyarrhythmias may all ... Recovery may take >1 ... Intraoperative #Checklist ... #Diagnosis #Management
Cardiac Arrest - Guidelines for Crises in Anaesthesia

The probable cause is one or more of: something
compressions 100 min-1, ... • As soon as ... reservoir bag and APL ... Anaphylaxis (→ 3-1) ... #Diagnosis #Management
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
adult, 10 ml.kg-1 ... • Also consider ... Anaphylaxis → 3-1 ... Intraoperative #Checklist ... #Diagnosis #Management