23 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... the study) • Triggers ... ATRA treatment Pathophysiology ... unless severe APLS ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... WBC >100k, + lab signs ... into serum • Triggers ... #diagnosis #management
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
compromise Clinical Signs ... be present or signs ... Pathophysiology: ... Coli, but can also ... Urine cultures also
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Diagnosis and Management ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... should be done in ALL
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... of UMN and LMN signs ... EMG: LMN Signs in ... neurology #diagnosis #management
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
of more of the signs ... chlorhexidine as ... re-administration of possible trigger ... #Anaphylaxis #Anesthesiology ... Checklist #Diagnosis #Management
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia
Causes: thrombus, fat, amniotic fluid, air/gas.
Signs: hypotension, tachycardia,
Signs: hypotension ... Also consider if ... mainstay of initial management ... mainstay of initial management ... Embolism #VTE #Anesthesiology
Local Anaesthetic Toxicity - Guidelines for Crises in Anaesthesia
Signs of severe toxicity:
 • Sudden alteration in
in Anaesthesia Signs ... tachyarrhythmias may all ... Anaesthetic #Toxicity #Anesthesiology ... Checklist #Diagnosis #Management
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... present, symptoms, signs ... symptoms (same as ... transformation into AML ... PV #Diagnosis #Management
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia

If the patient is unconscious, signs of cardiac
is unconscious, signs ... a 12-lead ECG as ... soon as possible ... Ischemia #Ischaemia #Anesthesiology ... Checklist #Diagnosis #Management