13 results
diagnosis neurology gh sclerosis acute als amyotrophic aortoenteric cop cryptogenic cystitis diabetes diabeticketoacidosis dka emphysematous excess feedbackloop fistula hematology hyperparathyroidism
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... metabolic abn #GrowthHormone ... #FeedbackLoop #endocrinology ... #pathophysiology
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Phosphate Physical Symptoms ... : Commonly no signs ... pain Psychiatric Symptoms ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... fraction • HTN #GrowthHormone ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Primary Hyperthyroidism ... Signs/Symptoms: ... Pretibial myxedema #Primary ... Hyperthyroidism #endocrinology ... #pathophysiology
Hypothyroid Myopathy Very common (up to 80% ) in patients with hypothyroidism Pathophysiology: • T4 deficiency leads to
hypothyroidism Pathophysiology ... impairs musde function ... Hypothyroid #Myopathy #pathophysiology ... #signs #symptoms ... #endocrinology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hyperviscosity syndrome • Triggers ... WBC >100k, + lab signs ... into serum • Triggers ... TLS #diagnosis #management
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
loss of motor function ... Bladder retention -> Primarily ... hemicord lesion -> Primarily ... Syndromes #diagnosis #pathophysiology ... #signs #symptoms
Emphysematous Cystitis Epidemiology: • Usually middle-aged diabetic women • Other RF: neurogenic bladder, urinary tract outlet obstruction,
compromise Clinical Signs ... /Symptoms: • Usually ... be present or signs ... Pathophysiology: ... also important Management
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Signs and symptoms ... Progressive MS • Primary ... Treatment: • Functionally ... disabling symptoms ... sclerosis #diagnosis #management
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
has good renal function ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
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