9 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
cells can go on to block ... exclusively affects black ... The underlying pathophysiology ... Can be triggered ... Features #Signs #Symptoms
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Guidelines for Crises ... Allergic reaction / anaphylaxis ... Phaeochromocytoma Neurologic ... Anesthesiology #Anesthesia #Checklist ... #Diagnosis #Management
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
Guidelines for Crises ... re-administration of possible trigger ... Guidelines for crises ... Intraoperative #Checklist ... #Diagnosis #Management
High Central Neuraxial Block - Guidelines for Crises in Anaesthesia
• Can occur with deliberate or accidental
Central Neuraxial Block ... Guidelines for Crises ... • Symptoms are ... Intraoperative #Checklist ... #Diagnosis #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
the study) • Triggers ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... PE, DAH, CHF, Anaphylaxis ... APML #diagnosis #management
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
Guidelines for Crises ... effects of neuraxial block ... ischaemia → 3-12 o Anaphylaxis ... Intraoperative #Checklist ... #Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
• Hypertensive crisis ... Etiology: • Pathophysiology ... Neurological symptoms ... Syndrome #diagnosis #management ... #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
infection that cross-reacts ... than one after symptom ... the underlying pathophysiology ... Syndrome #diagnosis #management ... #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Bilateral signs and/or symptoms ... than 2/3 of the cross-sectional ... Myelitis #diagnosis #management ... #neurology #differential