23 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
a Sickle Cell Crisis ... The underlying pathophysiology ... Can be triggered ... #Features #Signs ... #Symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... into serum • Triggers ... with tetany or cardiac ... TLS #diagnosis #management
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
-> GAS antigen cross-reacts ... to myosin and cardiac ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia

If the patient is unconscious, signs of cardiac
Guidelines for Crises ... is unconscious, signs ... is conscious, symptoms ... Intraoperative #Checklist ... #Diagnosis #Management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Guidelines for Crises ... (late sign) (→ ... Phaeochromocytoma Neurologic ... Anesthesiology #Anesthesia #Checklist ... #Diagnosis #Management
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia
Causes: thrombus, fat, amniotic fluid, air/gas.
Signs: hypotension, tachycardia,
Guidelines for Crises ... Signs: hypotension ... decreased ETCO2 Symptoms ... unexplained loss of cardiac ... Intraoperative #Checklist
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
Guidelines for Crises ... rise is a late sign ... dantrolene and cardiac ... Intraoperative #Checklist ... #Diagnosis #Management
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... /Symptoms/Exam findings ... - Erosions and crusts
Myasthenic Crisis Checklist - Myasthenia Gravis

Evaluation 
 - Chest X-ray and lung ultrasound (exclude other lung
Myasthenic Crisis ... Checklist - Myasthenia ... or TSH level if symptoms ... monitoring (vital signs ... #Management #CriticalCare
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
Guidelines for Crises ... of more of the signs ... re-administration of possible trigger ... Intraoperative #Checklist ... #Diagnosis #Management