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classification differential hematology hypersensitivity reactions aafp acidosis allergic antibiotics causes criticalcare definitions folate folicacid high homocysteine hyperkalemia lactate lactic macrocytic
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Mediator: lgE ... thrombocytopenia, Autoimmune Hemolytic ... anemia, Penicillin-induced ... Stevens-Johnson Syndrome ... #Diagnosis #Definitions
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
I - lgE-Mediated ... Hours to Days (Hemolytic ... Anemia) Type ... Classification #Allergy ... #Diagnosis
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy Mild Reaction - Itching, Minor rash
I (lgE-Mediated ... Stevens-Johnson syndrome ... systemic symptoms syndrome ... , Hemolytic anemia ... #Prescription #algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hematology for workup ... blood loss, Acute hemolysis ... , deficiency anemia ... Kawasaki, Nephrotic syndrome ... post-splenectomy, Exercise, Allergic
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... Hemorrhage or hemolysis ... of vitamin B12 are ... #Diagnosis #Macrocytosis ... #Workup #AAFP
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Mean age at Dx ... 70-75 years of age ... Workup: • Complete ... #diagnosis #hematology
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Shock, Severe Anemia ... Ischemia, Compartment Syndrome ... Beta-Agonists, ↑ work ... • Presents as AG ... in Short Bowel Syndrome
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
leukocytosis, in vitro hemolysis ... ), sickle cell anemia ... Pseudohypoaldosteronism type ... antiphospholipid syndrome ... #Differential #Diagnosis
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