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oncology rheumatology workup chronic cll differential disease leukemia lymphocytic management algorithm arthritis blood calcium cell deposition disorders gout hemeonc laboratory
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Even with normal WBC ... relative to both WBC ... 21% had normal WBC ... #neutrophil #WBC ... #CBC #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC ... Amy Chung, MD, MSc ... Blood #Disorders #hematology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
shoulders, wrists, elbows ... disease states Pathophysiology ... if < 50 Years Age ... #Gout #Comparison ... #rheumatology #
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... , smudge cells are ... Vmphocytosis on routine CBC ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
large numbers and are ... phenomenon CLL Diagnosis ... Lymphocytosis on CBC ... • Neutropenia, anemia ... workup #oncology #hematology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
) Pathophysiology ... shoulders, wrists, elbows ... if < 50 years age ... Synovial Fluid: • WBCs ... culture used to diagnose
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Complete blood count (CBC ... (to support a diagnosis ... laboratory #workup #diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
• Median age 50- ... Diagnosis? ... • No CRAB - no anemia ... • CBC + diff • ... #Workup #Hematology
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