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rheumatology management gout arthritis bandemia calcium cbc clinical degenerative deposition differential gouty hemeonc hemophagocytic hlh inflammatory jointdisease jointpain lymphohistiocytosis mri
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
shoulders, wrists, elbows ... • Underlying disease ... states Pathophysiology ... if < 50 Years Age ... #Gout #Comparison
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
(CPPD) Pathophysiology ... shoulders, wrists, elbows ... if < 50 years age ... #Rheumatology # ... diagnosis #management
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... These are CLASSIC ... Arthritides (RA, CPPD ... diffuse chondral disease ... #msk #rheumatology
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
mechanical forces that are ... #Degenerative #Comparison ... #Versus #MSK #JointDisease ... #JointPain #Diagnosis ... #pathophysiology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Band neutrophils are ... Differential Diagnosis ... • Autoimmune diseases ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Decades (can be any age ... Sjogren's Syndrome Diagnosis ... /aggregate) of CD4 ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
and treatment are ... ▪ Autoimmune diseases ... Pathophysiology ... of NK cells and CD8 ... #Management #Hematology
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